UniProtKB AC (Name) | UniProtKB Section | Organism | Description | |
---|---|---|---|---|
Q2G296 (FTHS_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Formate--tetrahydrofolate ligase; Formyltetrahydrofolate synthetase; | |
Q2G214 (MNHB2_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Putative antiporter subunit mnhB2; Mrp complex subunit B2; Putative NADH-ubiquinone oxidoreductase subunit mnhB2; | |
Q2FVC1 (PGCA_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Phosphoglucomutase; Alpha-phosphoglucomutase; Glucose phosphomutase; | |
Q2FZV2 (MNHB1_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Na(+)/H(+) antiporter subunit B1; Mnh complex subunit B1; | |
Q2G2R4 (LACA_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Galactose-6-phosphate isomerase subunit LacA; | |
Q2FXW1 (YQGF_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Putative pre-16S rRNA nuclease; | |
P0A088 (MSRB_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Peptide methionine sulfoxide reductase MsrB; Peptide-methionine (R)-S-oxide reductase; | |
Q2G0F8 (SYR_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Arginine--tRNA ligase; Arginyl-tRNA synthetase; | |
Q2FZ19 (RNJ2_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Ribonuclease J 2; | |
Q2FYZ4 (GLPD_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Aerobic glycerol-3-phosphate dehydrogenase; | |
Q2FWH9 (KDPA_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Potassium-transporting ATPase potassium-binding subunit; ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain; | |
Q2G1T3 (OHRL_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Organic hydroperoxide resistance protein-like; | |
P0A0F4 (RL11_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Large ribosomal subunit protein uL11; 50S ribosomal protein L11; | |
Q2FZ97 (MRAZ_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Transcriptional regulator MraZ; | |
Q2G0M6 (ARAB_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Ribulokinase; | |
Q2FYK4 (Y1436_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Bacilliredoxin SAOUHSC_01436; | |
Q2FY55 (Y1610_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Bacilliredoxin SAOUHSC_01610; | |
Q2G2E1 (MNHG2_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Putative antiporter subunit mnhG2; Mrp complex subunit G2; Putative NADH-ubiquinone oxidoreductase subunit mnhF2; | |
Q2G2K8 (UREE_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Urease accessory protein UreE; | |
Q2FXU2 (DTD_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | D-aminoacyl-tRNA deacylase; Gly-tRNA(Ala) deacylase; | |
Q2G2T3 (RL9_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Large ribosomal subunit protein bL9; 50S ribosomal protein L9; | |
Q2FY49 (ARGR_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Arginine repressor; | |
Q2FZ98 (BSHC_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Putative cysteine ligase BshC; | |
Q2FWF5 (FABZ_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Beta-hydroxyacyl-ACP dehydratase; | |
P72358 (LRGA_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Antiholin-like protein LrgA; | |
Q2FVQ7 (Y2645_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Uncharacterized HTH-type transcriptional regulator SAOUHSC_02645; | |
Q2G1Z4 (SYP_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Proline--tRNA ligase; Prolyl-tRNA synthetase; | |
Q2FV11 (BETA_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Oxygen-dependent choline dehydrogenase; Betaine aldehyde dehydrogenase; | |
Q2FWE3 (PTPB_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Low molecular weight protein-tyrosine-phosphatase PtpB; Phosphotyrosine phosphatase B; | |
Q2FWK7 (ILVD_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Dihydroxy-acid dehydratase; | |
Q2FXK8 (EZRA_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Septation ring formation regulator EzrA; | |
Q2FZG9 (RNJ1_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Ribonuclease J 1; | |
Q2FY19 (FUR_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Ferric uptake regulation protein; | |
Q2G2K6 (URE2_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Urease subunit beta; Urea amidohydrolase subunit beta; | |
Q2G2K5 (URE1_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Urease subunit alpha; Urea amidohydrolase subunit alpha; | |
Q2FZC0 (FLIPR_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | FPRL1 inhibitory protein; | |
Q2FYN3 (MSA_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Protein msa; Modulator of SarA; | |
Q2FZ95 (FTSL_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Cell division protein FtsL; | |
Q2G2M4 (MRNC_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Mini-ribonuclease 3; Mini-RNase III; | |
Q2FWF1 (ATPE_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | ATP synthase epsilon chain; ATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunit; | |
Q2G1M9 (SBNE_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | L-2,3-diaminopropanoate--citrate ligase; Staphyloferrin B biosynthesis protein SbnE; | |
Q2FWN4 (CH60_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Chaperonin GroEL; 60 kDa chaperonin; Chaperonin-60; | |
Q2FZZ8 (GCSH_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Glycine cleavage system H protein; Octanoyl/lipoyl carrier protein; | |
Q2FXZ2 (DNAK_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Chaperone protein DnaK; HSP70; Heat shock 70 kDa protein; Heat shock protein 70; | |
Q2FZD0 (UVRC_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | UvrABC system protein C; Excinuclease ABC subunit C; | |
Q2FV23 (PAND_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Aspartate 1-decarboxylase; Aspartate alpha-decarboxylase; Aspartate 1-decarboxylase beta chain; Aspartate 1-decarboxylase alpha chain; | |
Q2FXY7 (LEPA_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Elongation factor 4; Ribosomal back-translocase LepA; | |
Q2FZT3 (Y907_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | UPF0344 protein SAOUHSC_00907; | |
Q2FY45 (NUSB_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Transcription antitermination protein NusB; Antitermination factor NusB; | |
Q2FXU5 (SYD_STAA8) | Swiss-Prot | Staphylococcus aureus (strain NCTC 8325 / PS 47) | Aspartate--tRNA ligase; Aspartyl-tRNA synthetase; |
Staphylococcus aureus is a Gram-positive coccal bacterium that is a member of the Firmicutes, and is frequently found in the nose, respiratory tract, and on the skin. Although S. aureus is not always pathogenic, it is a common cause of skin infections such as abscesses, respiratory infections such as sinusitis, and food poisoning.
An estimated 20% of the human population are long-term carriers of S. aureus. It is one of the five most common causes of hospital-acquired infections and is often the cause of postsurgical wound infections. The emergence of antibiotic-resistant strains of S. aureus such as methicillin-resistant S. aureus (MRSA) is a worldwide problem in clinical medicine. There are currently (2016) no dedicated antibiotics against drug-resistant S. aureus available.
The genome of S. aureus was first sequenced in 2006.
From left to right: i) The number of proteins in the reference proteome of Staphylococcus aureus, ii) the number of unique protein sequences for which at least one model is available, iii) the total number of models and iv) a coverage bar plot is shown.
The bar plot shows the coverage for every protein in the reference proteome of Staphylococcus aureus for which there is at least one model. Different colours (dark green to red boxes) represent the coverage of the targets. Targets with high coverage are represented in dark green (more than 80% of the target's length is covered by models), whereas low coverage is shown in red. The size of each box is proportional to the number of target sequences with a given coverage.
For information on the latest proteome for Staphylococcus aureus, please visit UniProtKB.
You can easily download the latest protein sequences for Staphylococcus aureus proteome here. Please note this download is for the current UniProtKB release, which may be different to release 2024_02 that was used for the most up to date SWISS-MODEL Repository.
Proteins in proteome | Sequences modelled | Models |
2,889 | 2,347 | 3,751 |
Detailed coverage numbers are obtained by hovering the mouse over one of the boxes.
The plot shows the evolution over years (x-axis) of the fraction of Staphylococcus aureus reference proteome residues (y-axis) for which structural information is available. Different colors (light blue to dark blue) in the plot represent the quality of the sequence alignment between the reference proteome sequences (targets) and the sequences of the proteins in the structure database (templates). Alignments with low sequence identity are displayed in light blue, whereas alignments with high sequence identity are depicted in dark blue. The SWISS-MODEL Template Library is used as database of templates. Only target-template alignments found by HHblits and only residues with atom coordinates are considered.
This chart shows the percentage of residues in the Staphylococcus aureus proteome which are covered by experimental structures and the enhancement of coverage by homology modelling by the SWISS-MODEL pipeline. Experimental residue coverage is determined using SIFTS mapping. For residues which are not covered by experimental structures (including where there are no atom records in SIFTS mapping) the model coverage bars are coloured by QMEANDisCo local quality score.
Many proteins form oligomeric structures either by self-assembly (homo-oligomeric) or by assembly with other proteins (hetero-oligomeric) to accomplish their function. In SWISS-MODEL Repository, the quaternary structure annotation of the template is used to model the target sequence in its oligomeric form. Currently our method is limited to the modelling of homo-oligomeric assemblies. The oligomeric state of the template is only considered if the interface is conserved.
Single Chain | 2-mer | 3-mer | 4-mer | 5-mer | 6-mer | 7-mer | 8-mer | 9-mer | 10-mer | 12-mer | 13-mer | 14-mer | 21-mer | 24-mer | 25-mer | 40-mer | 60-mer |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2,387 | 949 | 75 | 190 | 6 | 80 | 6 | 18 | 2 | 7 | 13 | 3 | 4 | 1 | 7 | 1 | 1 | 1 |